Evaluation the Effect of Percutaneous Coronary Intervention of Left Anterior Descending Artery on Regional Myocardial Function Using Three-Dimensional Speckle Tracking Echocardiography

Abstract

Background: Percutaneous coronary intervention (PCI) is an established procedure for the treatment of coronary artery disease. The aim of this work is to evaluate the effect of PCI of left anterior descending artery on regional myocardial function using three-dimensional speckle tracking echocardiography.

Methods: This cohort study was conducted on 60 patients with chronic coronary syndrome (stable angina). All patients were subjected to general and local examinations, resting surface 12 ECG leads, laboratory analyses (low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol, triglycerides, and creatinine level) and 3D Echocardiography before and 6 weeks after PCI.

Results: There was a highly statistically significant difference between pre and post PCI according to LAD territory by AS with p-value (p<0.001). There was no statistically significant difference between pre and post PCI according to LAD territory by 2D CS and LAD territory by 3D CS. There was a statistically significant difference between pre and Post PCI according to LAD territory by 2D LS and 3D LS (p<0.001, P=0.012 respectively).

Conclusions: 3D-STE is a non-invasive applicable technique; it can detect changes of LV after revascularization even with normal ejection fraction.