Lavandula angustifolia Tea Extract Mediated Biosynthesis of Silver Nanoparticles and its biomedical potential

Abstract

Lavandula angustifolia flowers used in Lavender Tea is a good source of phytocompounds. In the present study, Lavandula angustifolia tea extract mediated silver nanoparticles (La-AgNPs) were biosynthesized and characterized by UV-Visible spectrometer, Fourier Transform Infrared spectrophotometer (FT-IR), Energy Dispersive X-Ray analysis (EDX) and Scanning Electron Microscopy (SEM). The colour changed from pale yellow to dark brown after and characteristic Surface Plasmon resonance (SPR) peak was observed at 445 nm in UV-vis spectrophotometer. (SEM) revealed the spherical morphology and ------ nm in size. (EDX) exhibited Carbon (18.6 Wt %), Oxygen (6.8 Wt %) and Silver as predominant element (74.6 Wt %). (FT-IR) showed the presence of phyto chemicals Amines, Alkanes, Alkenes, Alkynes, Alcohols, Halogens and Fluro compounds. Better Antimicrobial activity of La-AgNPs was found against Staphylococcus aureus (G +ve), Pseudomonas (G –ve) than Escherichia coli (G –ve) and Candida albicans. Increase in concentration of La-AgNPs revealed good antioxidant activity (80.60 % in 50 µL) concentration in DPPH Assay. Significant Anti-inflammatory activity was obtained (73.70 % in 50 µL) in Egg White Albumin Denaturation Assay. The cytotoxic effect showed 60 % of live Nauplii at 80 µL concentration in Brine Shrimp Lethality Assay. Therefore, La-AgNPs may be applicable as antimicrobial, antioxidant, anti-inflammatory and cytotoxic agents in nano biomedicine applications.