Rhabdomyolysis in COVID-19 Infection: A Systematic Review and Meta-Analysis


  • Shahaboddin Mashaei, Seyed Amir Ashkan Mousavi Chashmi, Solaleh Savoji, Rahele Alimoradzadeh, Salar Javanmard Barbin


COVID-19, Vital Signs, Survival Rate, Patient


Background and aim: the purpose of present study was evaluated Rhabdomyolysis in COVID-19.

Method: all articles published in international databases such as PubMed, Scopus, Science Direct, Embase between January 2019 and March 2022 included. Google Scholar search engine was used. Data analysis was performed using STATA.V16 software.

Result: In the initial search, 395 studies were identified; full text of 58 articles was reviewed; finally six articles entered the analysis. Meta-analysis showed 67% (MD; 95 CI (31%, 100%) requiring renal replacement therapy and 99% (MD; 95 CI (63%, 100%) Rhabdomyolysis patients had myalgias.

Conclusion: The findings of the present study showed that there is a direct correlation between myalgias and Covid-19; On the other hand, myalgias are one of the early signs of Rhabdomyolysis that should be carefully examined in patients with Covid-19 and Rhabdomyolysis should be suspected