Lung imaging features in COVID-19 cases: a systematic review and meta‐analysis


  • Elham Zarei, Zahra Haddadian, Asma Rostami, Elham Mohammadzadeh, Amirabbas Abdolhoseini


COVID-19, Computed tomography, Lung imaging features, Imaging manifestations, CT scan


Background and aim: the purpose of present study was evaluate Lung imaging features in COVID-19 cases.

Method: Current study following the PRISMA guidelines, all articles published in international databases such as PubMed, Scopus, Science Direct, Embase between January 2019 and March 2022 included. 95% confidence interval on effect size were done with random effect model and Restricted maximum-likelihood method. Data analysis was performed using STATA.V16 software.

Result: In the initial search, 759 studies were identified; full text of 207 articles was reviewed; finally 17 articles entered the analysis. Effect size of Abnormal chest CT of adult and pediatric COVID-19 patients was 2.55 (ES; 95 CI (2.18, 2.92)) and CI (0.53, 0.93)), respectively.  According to test of group differences, abnormal chest CT findings are more evident in adults. Ground Glass Opacity and Consolidation: Effect size of Ground Glass Opacity and Consolidation in pediatric COVID-19 patients was 0.47 (ES; 95 CI (-0.42, 1.36)) and Ground-glass opacity was 48 (ES; 95 CI (0.30, 0.66)).

Conclusion: Abnormal CT imaging was lower in the pediatric population than in adults with Covid-19. Ground Glass Opacity was more pronounced in both age groups. Further studies are needed to provide stronger evidence, especially in other parts of the world