Association between cardiovascular disease and severe COVID-19 and mortality rate in COVID-19 Patients: a systematic review and met analysis

Authors

  • Elham Mohammadzadeh, Zahra Azadifard, Iman Nosratabadi, Rahele Alimoradzadeh, Shima Sadat Aghahosseini

Keywords:

cardiovascular disease, COVID-19 mortality, COVID-19 disease

Abstract

Purpose: evaluate association between cardiovascular disease and severe COVID-19 and mortality rate in COVID-19 Patients.

Method: The present study is a systematic review and meta-analysis (PRISMA guidelines) study based on information collected from regular search of Internet resources using logical functions between keywords in PubMed, Scopus, Science Direct, Embase and scholar uses English keywords between January 2019 and March 2022. 95% confidence interval on odds ratio e were done with fixed effect model. Meta-analysis was performed using STATA.V16 software. 

Results: the full text of 161 articles was reviewed and finally 15 articles entered the analysis. Odds ratio of association between cardiovascular disease and severe COVID-19 and COVID-19 mortality was 1.05 (OR; 95% confidence interval 0.81 to 1.29; p=0.00) and 0.75 (OR; 95% confidence interval 0.44 to 1.06; p=0.00), respectively.

Conclusion: Meta-analysis shows that patients with cardiovascular disease are directly related to the progression of COVID-19 disease and COVID-19 mortality compared to the control group.

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Published

2022-04-12