Evaluate Crestal Bone Loss and Early Implant Losses in Immediate and Delayed Loading: A Systematic Review and Meta-Analysis


  • Parviz Amini, Neshat Atashpareh, Hamed Bahrami Maleki, Emad Yadshoghi Rashti, Sina Safari


Background and aim: the aim of current study was Evaluate crestal bone loss and early implant losses in immediate and delayed loading.

Methods: From the electronic databases, PubMed, Scopus, LILACS, Web of Science, EBSCO, LIVIVO, and Embase have been used to perform a systematic literature over the last twenty years between 2001 and September 2021.Odds ratio and mean differences with 95% confidence interval (CI), fixed effect model and Mantel-Haenszel or Inverse-variance method were calculated. The Meta analysis have been evaluated with the statistical software Stata/MP v.16 (The fastest version of Stata).

Results: 424 studies were selected to review the abstracts, the full text of 95 studies was reviewed. Finally, nine studies were selected. Odds ratio of early implant losses between delayed loading and immediate loading-0.95 (OR, -0.95 95 % CI -1.70, -0.19; p=0.01).

Conclusions: The quality of scientificevidence significantly favors delayed loading. Immediate loading significantly increased the risk of early implant losses.