Ophthalmic and Neurological Disorders in Patients with Giant Inactive Pituitary Adenomas Depending on the Nature of Tumor Growth

Abstract

68 patients with gigantic inactive adenomas of the pituitary gland were examined (from them men - 43, women -25). Middle age: men amounted to 37,12 years, women - 38, 15 years ago, the illness of the disease ranged from 2 months to 25 years.
Most often among patients met an endo-supraseller growth of the tumor -28 (41.1%). observations. The most pronounced violations of the visual fields in the form of amaurosis  and the bitemporal hemianopsy was observed in patients with endo-supraselligar growth - amaurosis (10.7%),  bitemporal  hemianopsy (89.3%), as well as with a total growth option - amaurosis (23%),  bitemporal hemianopsy (79.9%). The most pronounced neurological disorders in the form of hypotalamic-stem disturbances (pyramid symptoms, a decrease in reflexes and muscle tone diffuse) were observed in patients with a total growth option, with retrosellary growth and during germination in the brain.