To Evaluate the High and Low-Pressure Carbon Dioxide Impact in Patients Undergoing Laparoscopic Cholecystectomy


  • Dr. Teh Shin Chou, Dr. Manuja Pimplodkar, Dr. Nitin Nangare


Aim: The aim of the study to identify the High and Low-Pressure Carbon Dioxide impact In Patients Undergoing Laparoscopic Cholecystectomy.

Material and method: In this quasi-experimental clinical trial, 46 patients diagnosed with different intra-abdominal diseases were undergone laparoscopic surgeries under a standard of CO2 pressure (≥13 mmHg). In another group, 49 patients who were matched in age and gender were undergone laparoscopic surgeries under low CO2 pressure (≤12 mmHg). Results: The patients in both high and low CO2 pressure groups were comparable in age (37.66 vs. 42.38 years; P = 0.115), gender (P = 0.213), and operation time (36.17 vs. 34.65min), respectively. The patients underwent high CO2 pressure had significantly lower levels of diastolic BP after anesthesia (72.29 vs. 77.90; P = 0.021), lowest systolic BP (SBP) (94.70 vs. 102.27; P = 0.007), and lowest diastolic BP (DBP) (59.01 vs. 68.37; P < 0.002) in contrast with higher level of postoperative diastolic BP in high CO2 group (111.24 vs. 78.12; P < 0.002). SBP and DBP and heart rate were decreased significantly from preoperative to postanesthesia and postoperative surgery in groups.

Conclusion: Low CO2 pressure is recommended during laparoscopic surgeries as much as possible, especially in patients with comorbidities such as heart diseases, old ages, and for operations that take longer time.